Composition:
Orlisat 60 mg & 120 mg capsules.
Mechanism of Action:
Orlistat works by blocking the action of enzymes which break down fat. Fats in our diet cannot be absorbed unless broken down in to smaller components known as fatty acids. Orlistat prevents this breakdown of fat and the undigested fat is passed in the stool. This drug does not suppress appetite. It works within the gut and is not absorbed into the bloodstream.
Indications:
- Obesity management, including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet
- To reduce the risk for weight regain after prior weight loss
- For obese patients with an initial body mass index (BMI) = 30 kg/m2 or = 27 kg/m2 in the presence of other risk factors (e.g., hypertension, diabetes, dyslipidemia)
- Olisat 120 for obese patients and Olisat 60 for overweight patients
Sunday, July 27, 2008
OLISAT
GMAB Plus
Composition:
GLA 100mg + Methylcobalamin 1500 mcg + ALA 100 mg + Benfothiamine 100 mg + Ele. Zinc 15mg - Hard gelatin capsules
Mechanism of Action:
It is a multivitamin with mineral which acts as a secondary preventive agent.
Indications:
As a dietary/nutritional supplement in patients suffering from diabetes and cardiovascular diseases.
GLA 100mg + Methylcobalamin 1500 mcg + ALA 100 mg + Benfothiamine 100 mg + Ele. Zinc 15mg - Hard gelatin capsules
Mechanism of Action:
It is a multivitamin with mineral which acts as a secondary preventive agent.
Indications:
As a dietary/nutritional supplement in patients suffering from diabetes and cardiovascular diseases.
PIODART MF
Composition:
Pioglitazone 15 mg + metformin 500 mg tablets
Mechanism of Action:
Pioglitazone
Pioglitazone exerts its pharmacological effects by acting as a potent and highly selective agonist for the peroxisome proliferators activated receptor-gamma. Activation of these receptors promotes the transcription of several insulin responsive genes that help control lipid metabolism and glucose levels. It also reduces the insulin resistance in the periphery and in the liver of patients.
Metformin
Metformin decreases hepatic glucose production and intestinal absorption of glucose while improving insulin sensitivity.
Indications:
- In the treatment of type II diabetes mellitus
- Used when one anti-diabetes drug fails to control blood glucose level. This combination effectively reduces insulin resistance both at liver and peripheral tissues.
Pioglitazone 15 mg + metformin 500 mg tablets
Mechanism of Action:
Pioglitazone
Pioglitazone exerts its pharmacological effects by acting as a potent and highly selective agonist for the peroxisome proliferators activated receptor-gamma. Activation of these receptors promotes the transcription of several insulin responsive genes that help control lipid metabolism and glucose levels. It also reduces the insulin resistance in the periphery and in the liver of patients.
Metformin
Metformin decreases hepatic glucose production and intestinal absorption of glucose while improving insulin sensitivity.
Indications:
- In the treatment of type II diabetes mellitus
- Used when one anti-diabetes drug fails to control blood glucose level. This combination effectively reduces insulin resistance both at liver and peripheral tissues.
PIODART
Composition:
Pioglitazone 15 mg & 30 mg tablets
Mechanism of Action:
Pioglitazone exerts its pharmacological effects by acting as a potent and highly selective agonist for the peroxisome proliferators activated receptor-gamma. Activation of these receptors promotes the transcription of several insulin responsive genes that help control lipid metabolism and glucose levels. It also reduces insulin resistance in the periphery and in the liver of patients.
Indications:
- In the treatment of type II diabetes mellitus
- Improved Insulin action as well has favorable effects on lipid levels
Pioglitazone 15 mg & 30 mg tablets
Mechanism of Action:
Pioglitazone exerts its pharmacological effects by acting as a potent and highly selective agonist for the peroxisome proliferators activated receptor-gamma. Activation of these receptors promotes the transcription of several insulin responsive genes that help control lipid metabolism and glucose levels. It also reduces insulin resistance in the periphery and in the liver of patients.
Indications:
- In the treatment of type II diabetes mellitus
- Improved Insulin action as well has favorable effects on lipid levels
Metadoze IPR
Composition:
Metformin 850 mg tablets with IPR (Immediate and Patterned Release technology)
Mechanism of Action:
Metformin, belonging to the class of anti-diabetes drugs, Biguanide, improves insulin sensitivity. Its extra pancreatic actions include reduction of hepatic glucose production, potentiation of insulin actions, increased peripheral utilisation of glucose and delayed intestinal absorption of sugars and starches.
Indications:
- In the treatment of type II diabetes mellitus
- Used as a single drug or in combination with other drugs e.g. glimepiride, pioglitazone, etc. to control blood glucose levels
Metadoze IPR incorporates a unique technology which enables immediate and sustained release of Metformin. This not only makes Metformin longer acting, but also improves absorption and reduces side effects.
Metformin 850 mg tablets with IPR (Immediate and Patterned Release technology)
Mechanism of Action:
Metformin, belonging to the class of anti-diabetes drugs, Biguanide, improves insulin sensitivity. Its extra pancreatic actions include reduction of hepatic glucose production, potentiation of insulin actions, increased peripheral utilisation of glucose and delayed intestinal absorption of sugars and starches.
Indications:
- In the treatment of type II diabetes mellitus
- Used as a single drug or in combination with other drugs e.g. glimepiride, pioglitazone, etc. to control blood glucose levels
Metadoze IPR incorporates a unique technology which enables immediate and sustained release of Metformin. This not only makes Metformin longer acting, but also improves absorption and reduces side effects.
INSUGEN 50/50
Composition:
50% soluble and 50% NPH - 10ml vials of 40iu/ml strength
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30min-1 hr of injection. 30% soluble insulin gets its peak after 2 hrs of injection and 70% of NPH gets its peak after approx 6-8 hrs of injection, remaining in the body for about 10-12 hrs. Excretion is basically through the kidneys.
Indications:
- All types of diabetes mellitus.
- Taken as subcutaneous injection, can be given as once or twice daily.
- To keep blood glucose levels under control.
50% soluble and 50% NPH - 10ml vials of 40iu/ml strength
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30min-1 hr of injection. 30% soluble insulin gets its peak after 2 hrs of injection and 70% of NPH gets its peak after approx 6-8 hrs of injection, remaining in the body for about 10-12 hrs. Excretion is basically through the kidneys.
Indications:
- All types of diabetes mellitus.
- Taken as subcutaneous injection, can be given as once or twice daily.
- To keep blood glucose levels under control.
INSUGEN 30/70
Composition:
Insulin biphasic, 30% Soluble and 70% NPH - 10ml vials of 40iu/ml strength.
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30min-1 hr of injection. 30% soluble insulin achieves peak level after 2 hrs of injection and 70% of NPH achieves peak level after approx 6-8 hrs of injection, remaining in the body for about 10-12 hrs. Excretion is basically through the kidneys.
Indications:
- All types of diabetes mellitus.
- Taken as subcutaneous injection, can be given as once or twice daily.
- To keep blood glucose levels under control.
Insulin biphasic, 30% Soluble and 70% NPH - 10ml vials of 40iu/ml strength.
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30min-1 hr of injection. 30% soluble insulin achieves peak level after 2 hrs of injection and 70% of NPH achieves peak level after approx 6-8 hrs of injection, remaining in the body for about 10-12 hrs. Excretion is basically through the kidneys.
Indications:
- All types of diabetes mellitus.
- Taken as subcutaneous injection, can be given as once or twice daily.
- To keep blood glucose levels under control.
INSUGEN N
Composition:
Isophane (NPH) insulin - 10ml Vials of 40iu/ml strength
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. Used to maintain the basal level of insulin in the body. Starts working after approx 1-2 hrs of injection, gets the slight peak after 6-8 hrs and remains in the body for about 10-12 hrs.
Indications:
- All types of diabetes mellitus.
- Used to maintain fasting blood glucose level.
- Also known as bed time insulin.
- Taken as subcutaneous injection only.
INSUGEN R
Composition:
Soluble/ Regular Insulin - 10ml vials of 40iu/ml strength
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30 mins of injection and attains peak after 2 hrs, remaining in the body for upto 6-8 hrs.
Indications:
- All types of diabetes mellitus.
- For quick action and faster peak of insulin.
- Taken as subcutaneous injection to control post-meal surge in blood glucose.
- Also used in the ICUs and wards as IV (intravenous). Only insulin which can be given through IV.
Soluble/ Regular Insulin - 10ml vials of 40iu/ml strength
Mechanism of Action:
Insulin opens the cell receptors for glucose molecules to enter which in turn is utilized in the form of energy (ATP) to carry out the various activities by the body. It starts its action after 30 mins of injection and attains peak after 2 hrs, remaining in the body for upto 6-8 hrs.
Indications:
- All types of diabetes mellitus.
- For quick action and faster peak of insulin.
- Taken as subcutaneous injection to control post-meal surge in blood glucose.
- Also used in the ICUs and wards as IV (intravenous). Only insulin which can be given through IV.
Insulin
Insulin exerts effect on glucose metabolism by binding to Insulin receptors throughout the body. Upon binding, Insulin promotes the cellular uptake of glucose into fat and skeletal muscle and inhibits hepatic glucose output, thus lowering the blood glucose. Based on the time-action profile of Insulin, Biocon has developed two kinds of insulin:
1. Short acting – Insulin Regular – Used to control post-meal surge in glucose level
2. Intermediate/Longer acting- Insulin NPH- Used to control fasting glucose levels.
Insulin therapy involves patients taking these two types of Insulin one or many times during the day depending on the type and stage of diabetes. To enhance the convenience of therapy, we have combined the above types of Insulin, e.g. Insulin 30/70 containing 30% regular insulin and 70%, Insulin NPH and Insulin 50/50 containing 50% regular Insulin and 50% Insulin NPH.
1. Short acting – Insulin Regular – Used to control post-meal surge in glucose level
2. Intermediate/Longer acting- Insulin NPH- Used to control fasting glucose levels.
Insulin therapy involves patients taking these two types of Insulin one or many times during the day depending on the type and stage of diabetes. To enhance the convenience of therapy, we have combined the above types of Insulin, e.g. Insulin 30/70 containing 30% regular insulin and 70%, Insulin NPH and Insulin 50/50 containing 50% regular Insulin and 50% Insulin NPH.
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